SICKLE CELL DISEASE

Paper Topic: SICKLE CELL DISEASE

Your instructor will assign you a disease topic for your papers. Your references MUST include at least 5
recent primary research articles, 3 of which are from journals published by the American Physiological
Society (APS). There are 7 American Journal of Physiology (AJP) journals to choose from: Cell
Physiology; Endocrinology & Metabolism; Gastrointestinal & Liver Physiology; Heart & Circulatory
Physiology; Lung, Cellular & Molecular Physiology; Regulatory, Integrative & Comparative Physiology;
and Renal Physiology. In addition, there are a few other journals published by the APS that include
primary research that can be found here.

Writing the paper: SICKLE CELL DISEASE
Paper 2
Start the body of the paper on a new page after the title page. You should review current research on at
least five (5) pharmacological management options for the disease (from paper 1: Sickle Cell Disease)
including drugs in clinical trials. Your review should include these components:
1) The physiologic rationale for using the drugs in treating your assigned disease.
2) The mechanisms of action of these drugs.
3) The side effects of these drugs and their contraindications.
4) The dosages and routes of administration of the drugs.
This section must include a minimum of 5 unique references that are recent and the paper should be 3
pages long.

Figures
Figures are allowed in any section, but do not count towards page count. These can be your original
figures/drawings or (if properly cited) from one of your sources. Place all figures at the end of the paper.

Formatting the paper:
1) Student’s name must not appear anywhere on title page, paper, file name, or comments.
2) The title page for each paper should include the title of the entire project; course name, number,
and section number; professor’s name; and date. Title page does not count toward the page count.
3) Paper must be double-spaced, including between paragraphs. New paragraphs should be started
with a single tab.
4) Paper must have 1” margins on all sides.
5) Font must be 12 pt., Arial font (regular).
6) Minimum lengths refer to full pages; a full page is 23 lines of text. Do not use section headings for
“filler” as these will not count towards page count. Short or long papers will be penalized based on
the amount written/missing.
7) Direct quotations are not appropriate for this project; you are to write a paper, not copy and paste
from other papers.
8) All references must be professional peer-reviewed articles.
9) Your in-text citations and references need to be in current American Journal of Physiology – Cell
Physiology format. There is an EndNote template for this style; it is highly suggested that you use
it as you start doing research.